Safer Insecticides Development and Use: Development and Use [Hardcover]

Reference to the design of new insecticides nontoxic to the environment and the public emphasizing optimal food production with greater safety. Some 30 international experts examine topics including new types of active molecules among natural products and animal toxins; insect metabolic and organ syPreface -- Contributors -- 1. Introduction /Ernest Hodgson and Ronald J. Kuhr -- I. Introduction -- II. Factors Involved in Insecticide Development -- III. Approaches to the Development of Safer Insecticides -- IV. Summary and Conclusions -- 2. Metabolism of Xenobiotics /W. C. Dauterman and Ernest Hodgson -- I. Introduction -- II. Phase-I Reactions -- III. Phase-II Reactions -- IV. Nutritional Effects on Xenobiotic Metabolism -- V. Physiological Effects on Xenobiotic Metabolism -- VI. Genetic Effects on Xenobiotic Metabolism -- VII. Chemical Effects on Xenobiotic Metabolism -- 3. Quantitative Structure-Activity Relationships of Insecticides /Keiichiro Nishimura, Haiime lwamura, and Toshio Fuiita -- I. Introduction -- II. Quantitative Analysis of Structure-Activity Relationships -- III. Approaches Toward Safer Insecticides -- IV. Concluding Remarks -- 4. Endocrine-Based Insecticides /Thomas C. Sparks -- I. Introduction -- II. Physiological Approaches to Insecticide Selectivity -- III. Approaches to Discovering New Insecticides -- IV. Exploiting the Insect Endocrine System -- V. Endocrine-Based Insecticides: Potential Modes of Action -- VI. Conclusions -- 5. Nervous-System-Based Insecticides /Mohyee E. Eldefrawi and Amira T. Eldefrawi -- I. Introduction -- II. Voltage-Dependent Ion Channels -- III. Neurotransmitter Receptors -- IV. Neurotransmitter Synthesis and Release -- V. Termination of Neurotransmitter Action -- VI. Concluding Remarks -- 6. Insecticides Based on Differences in Metabolic Pathways /Richard T. Mayer, G. Cunningham, and J. Gupton -- I. Introduction -- II. Chitin Synthesis Inhibitors -- III. Prostaglandins -- IV. Steroid Analogs as Insect Molting Hormone Inl£p