Selenium in Biology and Medicine: Proceedings of the 4th International Symposium on Selenium in Biology and Medicine. Held July 18-21, 1988, T?bingen, [Paperback]

In July, 1988, more than 300 scientists from 29 different countries gathered at Tiibingen, W. Germany, in order to spend 4 days discussing their favourite trace element, selenium. This meeting continued the good tradition of three previous meetings held in Corvallis/Oregon, 1976, in Lubbock/Texas, 1980, and in Beijing/China, in 1984. Incidentally, the University of Tiibingen provided a unique historical background for a Symposium devoted to recent advances in biochemistry, pharmacology, human nutrition and human health; here, the first independent depart? ment of Physiological Chemistry in Germany was founded in 1845. Pro? fessor H9Ppe-Seyler elucidated here the hemin structure and his student Friedrich Miescher discovered the nucleic acids. This book contains one-half of the oral or poster presentations which were selected before the meeting was held on the basis of a one? page abstract. It is the reader who will have to decide whether this time? consuming policy of quality assessment was warranted or not.I Biochemistry of Selenoproteins and Selenium Compounds.- The Regulation of Glutathione Peroxidase Gene Expression; Implication for Species Difference and the Effect of Dietary Selenium Manipulation.- Regulation of Expression of Glutathione Peroxidase by Selenium.- Studies on New Selenoproteins and Specific Selenium Target Tissues.- Selenium-Containing Proteins in Plasma of Higher Primates.- Involvement of a Selenoprotein in Glycine, Sarcosine, and Betaine Reduction by Eubacterium acidaminophilum.- Dependence of Mouse Liver Phospholipid Hydroperoxide Glutathione Peroxidase on Dietary Selenium.- Interaction of Heparin with a Selenoprotein in Human Plasma.- Selenium-Independent Glutathione Peroxidase in Malaria Parasites.- Synthesis of a Selenium Analogue of Neurospora crassa Metallothionein and Its Properties.- Reactions of the Thioredoxin System with Selenium.- Selenite-Induced Variation of Glutathione Peroxidase Activity in Mammalian Cells and Its Consequences folÓÙ