This book represents a systematic and broadly based discussion and evaluation of the Gateway Hypothesis.This book represents a systematic and broadly based discussion and evaluation of the Gateway Hypothesis, according to which young people who progress in the use of drugs follow a specific sequence from the use of tobacco or alcohol to the use of illicit drugs to the use of illicit drugs other than marijuana. This volume evaluates the strengths and weaknesses of the hypothesis from multiple disciplinary perspectives representing sociology, psychology, epidemiology, statistics, animal behavior, molecular biology and prevention.This book represents a systematic and broadly based discussion and evaluation of the Gateway Hypothesis, according to which young people who progress in the use of drugs follow a specific sequence from the use of tobacco or alcohol to the use of illicit drugs to the use of illicit drugs other than marijuana. This volume evaluates the strengths and weaknesses of the hypothesis from multiple disciplinary perspectives representing sociology, psychology, epidemiology, statistics, animal behavior, molecular biology and prevention.This book represents a systematic and broadly based discussion and evaluation of the Gateway Hypothesis, according to which young people who progress in the use of drugs follow a specific sequence from the use of tobacco or alcohol to the use of illicit drugs to the use of illicit drugs other than marijuana. This volume evaluates the strengths and weaknesses of the hypothesis from multiple disciplinary perspectives representing sociology, psychology, epidemiology, statistics, animal behavior, molecular biology and prevention.Part I. Overview: 1. Examining the gateway hypothesis: stages and pathways of drug involvement Denise B. Kandel; Part II. Recent Substantive Findings: What Do We Know about Stages of Drug Use, Risks and Protective Factors?: 2. Drug sequences, age of onset and use trajectories as predictors of drug abuslĂ-