Sunlight, Vitamin D and Skin Cancer [Hardcover]

The goal of this volume is to comprehensively cover a highly readable, updated and extended, overview on our present knowledge of positive and negative effects of UVexposure, with a focus on vitamin D and skin cancer. Topics that are discussed indepth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of the second edition of this book to summarize essential uptodate information for every clinician or scientist interested in how to balance between positive and negative effects of UVexposure to minimize the risks of developing vitamin D deficiency and skin cancer.Sunlight, Ultraviolet-Radiation, Vitamin D and Skin Cancer: How Much Sunlight Do We Need?.- Vitamin D and Cancer: An Overview on Epidemiological Studies.- Vitamin D Status and Cancer Incidence and Mortality.- Solar Ultraviolet Irradiance and Cancer Incidence and Mortality.- Vitamin D Receptors Polymorphisms and Cancer.- The Role of Vitamin D for Cardiovascular Disease and Overall Mortality.- Epidemiology of Skin Cancer.- Histology of Melanoma and Nonmelanoma Skin Cancer.- Cytogenetics of Melanoma and Nonmelanoma Skin Cancer.- The Immune System and Skin Cancer.- Human Papillomaviruses and Skin Cancer.- Ultraviolet Damage, DNA Repair and Vitamin D in Nonmelanoma Skin Cancer and in Malignant Melanoma: An Update.- Molecular Biology of Basal and Squamous Cell Carcinomas.- Solar Ultraviolet-Radiation, Vitamin D and Skin Cancer Surveillance in Organ Transplant Recipients (OTRS): An Update.- Therapy of Metastatic Malignant Melanoma: On the Way to Individualized Disease Control.- The Vitamin D Receptor: A Tumor Suppressor in Skin.- ProteclÓ.