Transporters as Targets for Drugs [Hardcover]

In each volume of Transporters as Targets for Drugs an overview chapter introduces the newcomer to the topic covered. The series covers hot topics of frontier research summarized by reputed scientists in the field.

With contributions by numerous expertsOverview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and StructureActivity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.

M. Bingham S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte A.W. Ravna G. Sager S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock M.D. Andrews A.D. Brown P.V Fish A. Stobie F. Wakehut: Design of Monoamine Reuptake Inhibitors  SSRIs, SNRIs and NRIs

A. Hauck Newman J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaines Mechanism at the Dopamine Transporter

Z. Chen J. Yang P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni J. S?rensen H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges S.A. Patel: Pharmacology of Glutamatlƒ2