Vitamin D Analogs in Cancer Prevention and Therapy [Paperback]

A comprehensive, highly readable overview of the topics discussed at the First International Symposium on Vitamin D Analogs in Cancer Prevention and Therapy held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in  cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.

 

This volume provides a comprehensive, highly readable overview of the topics discussed at the First International Symposium on Vitamin D Analogs in Cancer Prevention and Therapy held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in  cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.1 Molecular Biology of Vitamin D.- Evolution and Function of Vitamin D.- Current Understanding of the Function of the Nuclear Vitamin D Receptor in Response to Its Natural and Synthetic Ligands.- Approaches to Evaluating the Association of Vitamin D Receptor Gene Polymorphisms with Breast Cancer Risk.- Ligand StructureFunction Relationships in the Vitamin D Endocrine System from the Perspective of Drug Development (Including Cancer Treatment).- Antiproliferative Signalling by 1,25(OH)2D3 in Prostate and Breast Cancer Is Suppressed by a Mechanism Involving Histone Deacetylation.- Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D CompoundslÓ*