The ACL Handbook Knee Biology, Mechanics, and Treatment [Hardcover]

The new age of biologic treatment of the ACL is coming.?In The ACL Handbook: Knee Biology, Mechanics, and Treatment, the authors cover the past and current state of ACL injuries and treatment, and then introduce and explain the key concepts for understanding the new biologic approach to ACL treatment.?The use of factors to enhance graft healing are reviewed, as well as an in-depth review of?the science of platelet-rich plasma and its cellular components (platelets, white cells, and plasma).?Chapters on in vitro models for science as well as the advantages and disadvantages of animal models for ACL research are included, as are chapters on the new technique of bio-enhanced ACL repair.?All?are discussed in easily readable text aimed at anyone with an interest of what is coming next in ACL surgery.

This book outlines the need for developing new treatments for ACL ruptures, covering the mechanics of the normal ACL and knee, the biology of the response to ACL injury, deficiencies in that response that make the ACL fail to heal spontaneously, and more.Part 1 - ACL Injury: The Clinical ProblemChapter 1 ACL Injury Epidemiology Patrick Vavken and Martha M. MurrayChapter 2 History of ACL Treatment and Current Gold Standard of Care
Martha M. MurrayChapter 3 ACL Clinical Outcomes Carolyn Hettrich and Kurt P. SpindlerChapter 4 ACL Treatment in the Skeletally Immature PatientPatrick Vavken and Martha M. MurrayPart 2 - ACL Injury: The Biologic ProblemChapter 5 The Biology of the Normal ACLMartha M. Murray and Braden C. FlemingChapter 6 The Role of Inflammation and Blood Cells in Wound HealingLinda H. Chao and Martha M. MurrayChapter 7 The ACL Response to InjuryMartha M. MurrayChapter 8 The Biology of Impaired Healing of Joint IssuesMartha M. MurrayPart 3 - Translational Medicine: In Vitro and In Vivo ModelsChapter 9 Translational MedicinePatrick VavkenChapter 10 In Vitro Models of ACL InjuryPatrick Vavken and Braden C. FlemingChaptels(