The Adenosine Receptors [Hardcover]

This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A₁, A_2A, A_2B and A₃. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntingtons disease, Epilepsy, Parkinsons disease and Alzheimers disease.

 

Historical Overview (Burnstock G.¹, & Abbracchio MP.²; ¹University College Medical School, London, UK;  ² University of Milan, Italy)

 

 

Thermodynamic Analysis of ARs (Borea PA. & Vincenzi F.; Department of Medical Sciences, University of Ferrara, Italy)

 

Medicinal Chemistry of A1 ARs (Scammels PJ., Medicinal Chemistry & Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Australia)