African horse sickness virus is a double-stranded RNA virus which causes a non-contagious, infectious arthropod-borne disease of equines and occasionally dogs. Nine distinct, internationally recognised serotypes of the virus have so far been identified.This book is based upon the findings of two programmes funded by the European Commission. It will be of value not only to the specialist research workers but also to veterinary workers dealing with control and tolegislators seeking to promote safe international movement of equines. The topics covered include state-of-the-art discussions on diagnostics, vaccines, molecular biology, vector studies, and epidemiology.African horse sickness virus is a double-stranded RNA virus which causes a non-contagious, infectious arthropod-borne disease of equines and occasionally dogs. Nine distinct, internationally recognised serotypes of the virus have so far been identified.This book is based upon the findings of two programmes funded by the European Commission. It will be of value not only to the specialist research workers but also to veterinary workers dealing with control and tolegislators seeking to promote safe international movement of equines. The topics covered include state-of-the-art discussions on diagnostics, vaccines, molecular biology, vector studies, and epidemiology.Epidemiology.- Taxonomy of African horse sickness viruses.- Epidemiology of African horse sickness and the role of the zebra in South Africa.- Transmission and distribution of African horse sickness virus serotypes in South African zebra.- Serological and virological responses in mules and donkeys following inoculation with African horse sickness virus serotype 4.- Donkeys as reservoirs of African horse sickness virus.- Clinical, virological and immune responses of normal and immunosuppressed donkeys (Equus asinus africanus) after inoculation with African horse sickness virus.- Immunohistochemical demonstration of African horse sickness viral antigenlsP