AIDS continually presents new questions for the obstetrician and gynecologist. The effect on pregnancy, the possibility of perinatal transmission, HIV positive tests, and risk to staff are just a few of the issues confronting clinicians and practitioners today. These and other questions were addressed by the 19th Study Group of the Royal College of Obstetricians and Gynaecologists, whose findings are reported here.Proceedings of the Nineteenth Study Group of the Royal College of Obstetricians and Gynaecologists, March 1988AIDS continually presents new questions for the obstetrician and gynecologist. The effect on pregnancy, the possibility of perinatal transmission, HIV positive tests, and risk to staff are just a few of the issues confronting clinicians and practitioners today. These and other questions were addressed by the 19th Study Group of the Royal College of Obstetricians and Gynaecologists, whose findings are reported here.Section I Epidemiology and Virology.- Virology.- The global patterns and prevalence of HIV infection in women.- Prediction of trends in AIDS incidence.- Discussion.- Heterosexual transmission of HIV.- Effects of human seminal plasma on the lymphocyte response to viral infection.- Discussion.- Section II Natural History.- The impact of pregnancy on HIV-related disease.- Infants born to mothers seropositive for HIV: results from the ongoing European Collaborative Study.- Paediatric AIDS in Uganda from materno-fetal infection.- Discussion.- HIV-1 infection in infants: practical laboratory diagnosis.- Subsequent care of infants of HIV positive mothers.- Discussion.- Section III Obstetric Management Problems.- Methods and reliability of antenatal diagnosis (including the effect of passive immunisation).- Antenatal HIV screeningethical considerations.- Discussion.- Counselling the HIV positive pregnant woman.- Termination of pregnancy.- Discussion.- Consumers concerns about AIDS.- Section IV Obstetric Care.- Changes in routine antenatl£Z