A comprehensive, practical and thought-provoking account of motor neuron disease.Amyotrophic lateral sclerosis / Lou Gehrig's or motor neuron disease is a degenerative disease of the aging nervous system. Drs Eisen and Krieger bring research expertise and extensive clinical experience to provide this practical and thought-provoking account.'The range of subjects covered is astonishing...their reviews are comprehensive and sophisticated. Their writing is clear and the several controversies are given balanced reviews. The ample illustrations have been selected thoughtfully... Anyone interested in ALS will find material for thought and for practice.' From the foreword by Professor L P RowlandAmyotrophic lateral sclerosis / Lou Gehrig's or motor neuron disease is a degenerative disease of the aging nervous system. Drs Eisen and Krieger bring research expertise and extensive clinical experience to provide this practical and thought-provoking account.'The range of subjects covered is astonishing...their reviews are comprehensive and sophisticated. Their writing is clear and the several controversies are given balanced reviews. The ample illustrations have been selected thoughtfully... Anyone interested in ALS will find material for thought and for practice.' From the foreword by Professor L P RowlandAmyotrophic Lateral Sclerosis, otherwise known as Lou Gehrig's Disease, is one of several degenerative diseases of the aging nervous system. This text neatly synthesizes the recent explosion of research into this particular condition to construct a detailed and comprehensive overview. Drs. Eisen and Krieger bring their research expertise and extensive clinical experience to provide this practical and thought-provoking account. Chapters cover the epidemiology, molecular biology, and pathophysiology of ALS, as well as issues pertinent to clinical assessment and care.Foreword; Preface; Acknowledgements; Abbreviations; 1. Epidemiological considerations; 2. The clinical spectrum ofl“…