This volume features a comprehensive set of protocols featuring a range of both old and new technologies that can be used to analyze drugs of abuse, including prescription drugs, new psychoactive substances and psychoactive plants. Chapters guide readers through the application of color tests, light microscopy-based particle imaging, GC-MS, Raman spectroscopy, capillary electrophoresis, ultra-high performance LC-tandem MS, DART-MS, MALDI-mass spectrometry imaging, LC-MS/MS and HPLC-ESI-MS/MS to the analysis of abused drugs in wastewater, hair, urine and plant-derived materials, among other matrices. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Analysis of Drugs of Abuse aims to ensure successful results in the further study of this vital field.
1. Color Tests for the Preliminary Identification of New Psychoactive Substances
Kaitlyn Toole, Morgan Philp, Nadine Krayem, Shanlin F, and Ronald Shimmon
2. Illicit and Counterfeit Drug Analysis by Morphologically Directed Raman Spectroscopy
Andrew C. Koutrakos, Pauline E. Leary, and Brooke W. Kammrath
3. Analysis of Drugs of Abuse by Gas Chromatography-Mass Spectrometry (GC-MS)
Thomas A. Brettell and Benny J. Lum
4. Towards Confirmatory On-site Real-Time Detection of Emerging l“'