Analysis of Genes and Genomes [Paperback]

This beautifully illustrated textbook provides a clear guide to the tools and techniques of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented.

Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics.

• A modern post-genome era introduction to key techniques used in genetic engineering.
• An example driven past-to-present approach to allow the experiments of today to be placed in an historical context
• The book is beautifully illustrated in full-colour throughout.
• Associated website including updates, additional content and illusions 

Preface.

Acknowledgements.

Dedication.

1. DNA: structure and function.

1.1 Nucleic acid is the material of heredity.

1.2 Structure of nucleic acids.

1.3 The double helix.

1.4 Reversible denaturing of DNA.

1.5 Structure of DNA in the cell.

1.6 The eukaryotic nucleosome.

1.7 The replication of DNA.

1.8 DNA polymerases.

1.9 The replication process.

1.10 Recombination.

1.11 Genes and genomes.

1.12 Genes within a genome.

1.13 Transcription.

1.14 RNA processing.

1.15 Translation.

2. Basic technil“M