Analysis of Nucleic Acids by Capillary Electrophoresis [Paperback]

Die Kapillarelektrophorese (CE) ist heute in biochemischen Laboratorien noch nicht als Routinemethode zur DNA-Trennung etabliert, obwohl sie diverse Vorz?ge gegen?ber den derzeitigen Methoden besitzt.
In diesem Band stellen verschiedene Wissenschaftler die theoretischen Aspekte der Trennung von Oligonucleins?uren mit der CE, die instrumentellen Grundlagen und deren Grenzen und schlie?lich die praktische Anwendung in der Biochemie und Molekularbiologie vor.

This book on capillary electrophoresis is unique in its focus on the separation of nucleic acids. The importance of electrophoretic separation in every molecular biology laboratory justifies this specialization, which is also reflected in the development of instrumentation.
This book is aimed to help to implement this rather new and promising technology in the biological laboratories and to help to overcome typical problems that can occur when starting with a new technique. It should also trigger further development in the field. It covers the theoretical background as well as practical examples of usual applications.
The authors are all experts in their field, having many years of experience with capillary electrophoresis and their application to nucleic acids.During the last decade, capillary electrophoresis has been developed into a very powerful analytical technique, which has many advantages over conventional slab gel techniques. The improvement is comparable to the one occuring earlier in the field of chromatography, with the introduction of the high performance technology. How important this technique has be? come, is reflected by the shear volume of papers published each month; as well as a dozen of books already published on this subject. One of the most important conferences in the field, the International Symposium on High Performance Capillary Electrophoresis attracts now nearly thousand people every year. As capillary electrophoresis can be applied to malc<