This volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.
1. Proteomic Analysis of Post-Translational Modifications in Neurobiology
Hongbo Gu, Matthew P. Stokes, and Jeffrey C. Silva
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2.? A Boronic Acid-based Enrichment for Site-specific Identification of the N-glycoproteome using MS-based Proteomics
Haopeng Xiao, George X. Tang, Weixuan Chen, and Ronghu Wu
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3. Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry
Chenxi Jia, Christopher B. Lietz, Qing Yu, and Lingjun Li
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4. Quantitative Profiling of Reversible Cysteome Modification under Nitrosative Stress
Yue-Ting Wang, Sujeewa C. Piyankarage, and Gregory R. J. Thatcher
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5. Label-free LC-MS/MS Comparative Analysis of Protein S-nitrosome in Synaptosomes from?Wild Type and APP Transgenic Mice
Monika Zarba-KozioB, Maciej Lalowski, and Aleksandra WysBouch-CieszyDsklã#