Androgens in Health and Disease [Paperback]

Authoritative researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Topics range from explaining the biology of androgens-from several different perspectives-to illuminating their role in the development and modulation of physiologic systems. Authors demonstrate in a number of cases that testosterone can be a useful adjunct to the treatment of a variety of disease states. Other chapters consider important topics such as androgens use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives.Authoritative researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Topics range from explaining the biology of androgens-from several different perspectives-to illuminating their role in the development and modulation of physiologic systems. Authors demonstrate in a number of cases that testosterone can be a useful adjunct to the treatment of a variety of disease states. Other chapters consider important topics such as androgens use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives.I. General AndrologyTestosterone Synthesis, Transport, and MetabolismStephen J. Winters and Barbara J. ClarkAndrogen ActionTerry R. BrownHypogonadism in Men: An OverviewStephen R. PlymateDihydrotestosterone and 5a-Reductase: Normal Physiology and InhibitionPaul R. Sutton, John K. Amory, and Richard V. ClarkEstrogen Action in Males: Insights Through Mutations in Aromatase and Estrogen-Receptor GenesJonathan Lindzey and Kenneth S. KorachAlterations of Androgen Action Caused by Mutation of the Human Androgen ReceptorMichael J. McPhaulAndrogen Excess Disorders in WomenRichard S. LegroAndrogen Pharmacology and Delivery SystemsChristina Wang and Ronald S. SwerdloffII. Androgen Effects on Physioll3#