Anti-Idiotypes, Receptors, and Molecular Mimicry [Paperback]

Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin action, thyroid cell function, the neurosciences, cardiology, virology, pharmacology, and reproduction. Proceedings of a Pre-Congress Symposium Held in Quebec, June 28 - July 1, 1986, in Conjunction with the Sixth Inter- national Congress of Immunology Held in TorontoHere is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin action, thyroid cell function, the neurosciences, cardiology, virology, pharmacology, and reproduction. Idiotypes, Paratopes, and Molecular Mimicry.- Functional Heterogeneity of Anti-Idiotype Antibodies.- Comparison of the Anti-PC Response to Nominal and Idiotope Antigens.- Anti-Idiotypes as Probes of Immunoglobulin Structure.- A Molecular Recognition Code: Its Use for the Purification of ACTH, Endorphin, and LHRH Receptors.- Anti-idiotypic Antibodies and Substance P Receptors.- Anti-idiotypic Antibodies Approach to the Study of the TSH Receptor.- Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insl8