Apoptosis [Paperback]

Apoptosis plays a central role in the regulation of cell proliferation. Disruption of this control mechanism may cause serious human diseases such as encephalomyelitis and cancer. Thus, understanding of the molecular mechanisms of apoptotic cell death should lead to fundamental advances in the therapy of these diseases.
Apoptosis plays a central role in the regulation of cell proliferation. Disruption of this control mechanism may cause serious human diseases such as encephalomyelitis and cancer. Thus, understanding of the molecular mechanisms of apoptotic cell death should lead to fundamental advances in the therapy of these diseases.
An Endonuclease Responsible for Apoptosis.- 1 Introduction.- 2 Results.- 3 Discussion.- References.- Cytopathic Feline Leukemia Viruses Cause Apoptosis in Hemolymphatic Cells.- Abstract.- 1 Introduction.- 2 Cytopathic Infections with FeLV-C in Vivo and Direct Induction of Apoptosis in T4 Cells by FeLV-C.- 3 Killing of Lymphocytes by FeLV-FAIDS/p61C and Associated Variants.- 4 FeLV-C-Related Nonregenerative Anemia: Potential Role for Apoptosis.- 5 FeLV Genes Important in Cytopathicity/Apoptosis Induction.- 5.1 General Remarks.- 5.2 T-Cell Killing.- 5.3 Erythroid Aplasias.- 6 Speculative Relationship to Endogenous Virus Recombinants and Importance Across Evolution.- 7 Regions of FeLV p15E Important in Immunosuppression.- 8 Other Types of Cytopathic Disease Seen in Viremic Cats Which Could Have an Apoptotic Basis.- 8.1 Enteritis.- 8.2 Infertility and Abortion.- 8.3 Neurologic Syndrome.- 9 So How Does FeLV Cause Apoptosis?.- 10 Other Retroviruses and Animal Viruses as Potential Causes of Apoptosis.- 10.1 Retroviruses that Behave as Superantigens.- 10.2 HIV and Other Lentiviruses.- 10.3 Chicken Anemia Virus.- References.- Neurotoxicity in Rat Cortical Cells Caused by N-Methyl-D-Aspartate (NMDA) and gp120 of HIV-1: Induction and Pharmacological Intervention.- Abstract.- 1 Introduction.- 2 Induction of Apoptosis in Rat Cortlƒ-