The Beginnings of Cancer in the Cell An Interdisciplinary Approach [Paperback]

Initiation of cancer in the cell is experimentally related to action of chemicals and radiation. For understanding the first steps of this interaction, approved methods from quantum theory and solid state physics are applied by the authors.
The approach of this book is interdisciplinary. Theoretical models are qualitatively applied. Known effects, like oncogene activation, anti-oncogenes, and disturbances of the cell's self-regulation are explained. The authors propose possible points of intervention in the cancer initiation process based on the theoretical considerations.
Initiation of cancer in the cell is experimentally related to action of chemicals and radiation. For understanding the first steps of this interaction, approved methods from quantum theory and solid state physics are applied by the authors.
The approach of this book is interdisciplinary. Theoretical models are qualitatively applied. Known effects, like oncogene activation, anti-oncogenes, and disturbances of the cell's self-regulation are explained. The authors propose possible points of intervention in the cancer initiation process based on the theoretical considerations.
Preface.- (The History of Cancer).- References.- 1 Do We Carry the Cause of Cancer in Our Genes?.- 1.1 Viral Cancer Causing Genes.- 1.2 Oncogenes in Plants and Animals.- 1.3 Human Cancer Causing Genes.- References.- 2 Activation of Cancer-Causing Genes (Biochemical Discussion).- 2.1 Activation of Oncogenes Through Mutations.- 2.2 Overactivation of Some Normal Genes.- 2.2.1 Overactivation by DNA Segments of Viral Origin.- 2.2.2 Translocation of Genes.- 2.3 Other Biochemical Possibilities of Oncogene Activation.- 2.3.1 Amplification.- 2.3.2 Antioncogene Deactivation.- 2.3.3 DNA Transposition.- References.- 3 The Role of External Factors in the Start of the Cancerous Change in a Cell.- 3.1 Different Cancer Initiating Chemical Compounds (Carcinogens) and Their Most Important Reactions in the Cell.ls.