Experimental investigations in the past 10-15 years have provided convincing evidence of the cancer preventive potential of berries. Berries and their components have been shown to reduce the malignant properties of cancer cells in culture by influencing genes associated with cancer development. In addition, diets containing freeze-dried berries have been shown to prevent cancer in animals, and recent data indicate that they also exhibit cancer preventive effects in humans.
Berries and their constituents have been shown to reduce the malignant properties of cancer cells in culture by influencing genes associated with cancer development. This volume describes berries bioactive compounds and their effects in animals and humans.
Berries and Cancer PreventionI. Berry composition, bioavailability, metabolism and biological effects1.Contribution of berry anthocyanins to their chemopreventive properties - Pu Jing and M. Monica Giusti2.Ursolic acid and other pentacyclic triterpenoids: Anticancer activities and occurrence in berries - Catherine C. Neto3.Biological effects of berry extracts on carcinogenic signaling pathways in vitro - Tongjian Cai and Chuanshu HuangII. Antioxidant capacity of berry components4.Correlation of antioxidants and antioxidant enzymes to oxygen radical scavenging activities in berries - Shiow Y. WangIII. Chemopreventive effects of berries and berry components in animal model systems5.Berries and the prevention of esophageal adenocarcinoma - Laura A. Kresty, Amy Exum and Bree Zeyzus-Johns6.Endothelial cell tumor prevention with berry extracts: Clinical problems, molecular mechanisms and therapeutic opportunities - Gayle M. Gordillo, Chandan K. Sen7.Effects of black raspberries on UV-induced cutaneous inflammation and tumor development - Tatiana M. Oberyszyn8.Chemopreventive effects of berries and berry components in the rodent esophagus - Claire Seguin, Li-Shu Wang, and Gary Stoner9.Prevention of estrogen-mediated mammary tumorslÃ-