Bioinformatics and Drug Discovery [Hardcover]

Recent advances in drug discovery have been rapid. ?The second edition of ?Bioinformatics and Drug Discovery has been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis. Each chapter provides an extended introduction that describes the theory and application of the technology. In the second part of each chapter,? detailed procedures related to the use of these technologies and software have been incorporated. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

Thorough and intuitive, Bioinformatics and Drug Discovery, Second Edition ?seeks to aid scientists in the further study of the rapidly expanding field of drug discovery.

The 2nd edition of this Methods in Molecular Biology book covers new techniques in target identification, genomic analysis, cheminformatics, protein analysis and network or pathway analysis. Includes detailed advice on getting optimal laboratory results.

1. Cell Perturbation Screens for Target Identification by RNAi

Kubilay Demir and Michael Boutros

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2. Using Functional Genomics to Identify Drug Targets: a Dupuytrens Disease Example

Mirela Sedic, Sandra Kraljevic Pavelic, Karlo Hock

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3. Functional Characterization of Human Genes from Exon Expression and RNA Interference Results

Dorothea Emig, Hagen Blankenburg, Fidel Ram?rez, and Mario Albrecht

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4. Barcode Sequencing for Understanding Drug-gene Interactions

Andrew M. Smith, Tanja Durbic, Saranya? Kittanakl37