Biological Aging Methods and Protocols [Hardcover]

This book investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions.

Biological Aging: Methods and Protocols investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. The editors have carefully selected only those topics that are considered mainstays of the field or are showing promise in revolutionizing this relatively new science. The three main areas of focus in this cutting-edge compendium of biological aging research are: methods that are basic to understanding the fundamental mechanisms of cellular aging; techniques used to intervene in the aging process; and approaches to analyzing the many molecular processes of biological aging. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions in the exciting and expanding field of biological aging.

Contents:PrefaceContributorsTechniques for Analysis of Biological AgingTrygve O. TollefsbolAging Cell Culture: Methods and ObservationsSharla M. O. Phipps, Joel B. Berletch, Lucy G. Andrews,and Trygve O. TollefsbolMethods to Detect Biomarkers of Cellular Senescence: The Senescence Associated b-galactosidaseKoji Itahana, Judith Campisi, and Goberdhan P. DimriMethods of Cell Sorting of Young and Senescent CellsJoao F. Passos and Thomas von ZglinickiTelomere Length AnalysisAndres Canela, Peter Klatt, and Maria A. BlalÃ