Bone Resorption [Hardcover]

There is currently no single book with up to date information on osteoclast function and bone resorption.

A useful collection of information, not readily available in a concentrated and convenient form on the market.

Provides a comprehensive overview of the field.

Preface 1. Osteoclast: Origin and DifferentiationJanet Rubin and Edward M. Greenfield 2. Osteolytic Enzymes of OsteoclastsMerry Jo Oursler 3. The Regulation of Osteoclast ActivityRoland Baron and William C. Horne 4. Structural Aspects of Bone ResorptionSteven D. Bain and Ted S. Gross 5. Inflammatory CytokinesMark S. Nanes and Roberto Pacifici 6. Genetics and Mutations Affecting Osteoclast Development and FunctionMark C. Horowitz, Melissa A. Kacena, Joseph A. Lorenzo 7. Clinical Disorders Associated With Alterations in Bone ResorptionJanet Rubin and Mark S. Nanes 8. Pharmaceuticals for Bone Disease Targeting the OsteoclastLorraine A. Fitzpatrick 9. Skeletal Complications of Malignancy: Central Role for the OsteoclastGregory A. Clines, John M. Chirgwin, Theresa A. Guise Index

From the reviews:

Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists. (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005)

Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgel“M