Cancer Genomics and Proteomics Methods and Protocols [Hardcover]

Cancer Genomics and Proteomics: Methods and Protocols, Second Edition?includes methods for the analyses of cancer genome and proteome that have illuminated us about the changes in cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Cancer Genomics and Proteomics: Methods and Protocols, Second Edition seeks to aid scientists in the further study into various aspects of tumor initiation and progression.

1. Genome-Wide Mapping Of RNA Pol-II Promoter Usage In Mouse Tissues By Chip-Seq

Sharmistha Pal, Ravi Gupta And Ramana V. Davuluri

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2. Using Native Chromatin Immunoprecipitation To Interrogate Histone Variant Protein Deposition In Embryonic Stem Cells

Zito Tseng, Tao Wu, Yifei Liu, Mei Zhong, And Andrew Xiao

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3. Reduced Representation Bisulfite Sequencing To Identify Global Alteration In The DNA Methylation

Arvindhan Nagarajan, Christine Roden And Narendra Wajapeyee

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4. A High-Throughput Microrna Expression Profiling System

Yanwen Guo, Stephen Mastriano And Jun Lu

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5. Using Pooled Mir30-Shrna Library For Cancer Lethal And Synthetic Lethal Screens

Liam Changwoo Lee, Shaojian Gao, Qiuning Li, And Ji Luo

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6. Genome-Wide RNA Interference Screening To Identify Regulators Of Epigenetic Silencing Of A Tumor Suppressor Gene

Matteo Forloni, Thuy Ho And Narendra Wajapeyee

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