Cellular Mechanisms in Airways Inflammation [Paperback]

Airways inflammation is a complex biological phenomenon resulting fromthe recruitment and activation of numerous cell types. Airwaysinflammation contributes to the pathophysiology of airways disease. Anunderstanding of the mechanisms that regulate inflammatory cell functionis essential for the development of novel anti-inflammatory drugs forthe treatment of common respiratory diseases such as asthma and COPD.This book provides a collection of valuable reviews on the majorinflammatory cells involved in airways disease and examines thepharmacology of current anti-inflammatory drugs used in the treatment ofairways disease. Moreover, an insight into the development of emergingdrug therapies is also highlighted.This book is a must for the library of any researcher or clinicianinterested in the pathophysiology of airways disease.Airways inflammation is a complex biological phenomenon resulting fromthe recruitment and activation of numerous cell types. Airwaysinflammation contributes to the pathophysiology of airways disease. Anunderstanding of the mechanisms that regulate inflammatory cell functionis essential for the development of novel anti-inflammatory drugs forthe treatment of common respiratory diseases such as asthma and COPD.This book provides a collection of valuable reviews on the majorinflammatory cells involved in airways disease and examines thepharmacology of current anti-inflammatory drugs used in the treatment ofairways disease. Moreover, an insight into the development of emergingdrug therapies is also highlighted.This book is a must for the library of any researcher or clinicianinterested in the pathophysiology of airways disease.Pathological spectrum of airway inflammation.- Role of basophils in airways inflammation.- Platelets.- Neutrophils.- Eosinophils in asthma.- Fibroblasts and myofibroblasts.- Airway macrophages and dendritic cells.- Contribution of endothelial cells to airway inflammation.- Airway epithelial cells.- Airway smooth muscle cellsl3y