Chronic Medical Disease and Cognitive Aging: Toward a Healthy Body and Brainexplores the important and often overlooked connection between how chronic medical diseases of the body can affect cognitive function and brain health. As population demographics shift to that of an aging population it has become more important to understand and improve cognitive function in late life. Chronic medical diseases often increase the risk of cognitive impairment, and those with cognitive impairment may be less able to effectively manage their medical conditions, suggesting a reciprocal relationship may exist where medical disease impacts cognition that in turn may exacerbate physical health.
Chronic Medical Disease and Cognitive Agingdiscusses current research on the association between a variety of chronic medical diseases and cognition and, where appropriate, promising interventions or accepted treatment strategies. While a cure for many diseases continues to be elusive, insights garnered from the interplay between diseases of the body and mind may help point the way to novel therapeutic strategies to improve cognitive function in late life.
Introduction Kristine Yaffe, MD Chapter 1 Epidemiological insights into blood pressure and cognitive disorders Lenore J. Launder, PhD Chapter 2 Cholesterol, Statins, and Late-life cognitive disorders Alina Solomon, MD, PhD and Miia Kivipelto, MD, PhD Chapter 3 Cardiovascular Disease and Cognitive Aging Angela L. Jefferson, PhD, and Melissa Thompson, DVM Chapter 4 Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu over the Lifecourse Rachel A. Whitmer, PhD and Deborah R. Gustafson, MS, PhD Chapter 5 Insulin Resistance and Pathological Brain Aging Brenna Cholerton, PhD, Laura D. Baker, Ph.D., and Suzanne Craft, PhD Chapter 6 Metabolic Syndrome, other Composite Vascular Risk Scores, and Cognitive Impairment Jos? Alejandro Luchsinger, MD, MPH Chapter 7 Chronic Kidney Dlsą