This volume provides broad coverage of computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those concerned with general techniques and concepts that apply to all organisms to others that are more specialized, covering specific biological systems such as viruses, Drosophila, and Homo sapiens. Written in the highly successful Methods in Molecular Biology series format, by authors who are active researchers in the field, many chapters include step-by-step procedures, which illustrate practical applications of the techniques described.
Cutting-edge and thorough, Comparative Genomics: Methods and Protocols should be useful to students and researchers in the continually growing and exciting field of comparative genomics.
Preface&
Table of Contents&
Contributing Authors&
1. Gene Phyologenies and Orthologous Groups
Jo?o C. Setubal and Peter F. Stadler
2. Pan-Genome Storage and Analysis Techniques
Tina Zekic, Guillaume Holley, and Jens Stoye
3. Comparative Genomics for Prokaryotes
Jo?o C. Setubal, Nalvo Almeida, and Alice R. Wattam
4. Assembly, Annotation and Comparative Genomics in PATRIC, the All Bacterial Bioinformatics Resource Center
Alice R. Wattam, Thomas Brettin, James J. Davis, Svetlana Gerdes, Ronald Kenyon, Dustin Machi, Chunhong Mao, Robert Olson, Ross Overbeek, Gordon D. Pusch, Maulik P. Shukla, Rick Stevens, Veronika Vonstein, Andrew Warren, Fangfang Xia, and Hyunseung Yoo
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