Detection of Biological Agents for the Prevention of Bioterrorism [Paperback]

The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available.This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contributions general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.

This volume presents an overview of mass spectrometry (MS) as a means to detect & identify biological and chemical threats. The text provides readers with an understanding of the latest MS developments in the cutting-edge fields of MS-biodefense technologies.

Preface.- Broadband analysis of bioagents by mass spectrometry; C. Fenselau et al.- Hollow-fiber flow field-flow fractionation for mass spectrometry: from proteins to whole bacteria; P. Reschiglian et al.- Mass spectrometry and tandem mass spectrometry for protein biomarker discovery and bacterial speciation; A. Fox, K. Fox.- Intact cell/spore mass spectrometry of fusarium macro conidia for fast isolate and species differentiation; H. Dong et al.- Bacteriophage amplification-coupled detection and identification of bacterial pathogens; C.R. Cox, K.J. Voorhees.- Matrix assisted laser desorption ionization mass spectrometric analysis of bacillus anthracis: from fingerprint analysis of the bacterium to quantification of its toxins in clinical samples; A.R. Woolfitt et al.- MiclC$