Early Clinical Intervention and Prevention in Schizophrenia [Paperback]

Leading and internationally recognized researchers review what is known about the liability to schizophrenia, how it progresses, what it looks like clinically-with an emphasis on a specific (proposed) syndrome of liability (schizotaxia)-and how best it might be treated now and in the near future. The authors summarize the latest findings on the genetic, early environmental, and neurodevelopmental origins of schizophrenia.Leading and internationally recognized researchers review what is known about the liability to schizophrenia, how it progresses, what it looks like clinically-with an emphasis on a specific (proposed) syndrome of liability (schizotaxia)-and how best it might be treated now and in the near future. The authors summarize the latest findings on the genetic, early environmental, and neurodevelopmental origins of schizophrenia.Part I. The Etiology and Genetics of SchizophreniaThe Genetic Basis of SchizophreniaStephen V. Faraone, Stephen J. Glatt, and Levi TaylorEarly Environmental Determinants of SchizophreniaJason Schiffman, John Carter, Ricardo A. Mach?n, and Sarnoff MednickObstetric Risk Factors for Schizophrenia and Their Relationship to Genetic Predisposition: Following Ariadne's Double-Stranded Thread Through Early DevelopmentStefano Marenco and Daniel R. WeinbergerPart II. The Vulnerability to SchizophreniaThe Nature of the Prodrome in SchizophreniaJaak Rakfeldt and Thomas H. McGlashanThe Nature of SchizotaxiaStephen V. Faraone, Ming T. Tsuang, and Sarah I. TarboxA Neuropsychological Perspective on Vulnerability to Schizophrenia: Lessons From High-Risk StudiesAllan F. Mirsky and Connie C. DuncanNeurocognitive Deficits in the Biological Relatives of Individuals With SchizophreniaWilliam S. Kremen and Anne L. HoffThe Nature and Origin of Socioemotional Deficits in SchizophreniaElaine Walker and Karen M. HochmanNeuroimaging Studies of Nonpsychotic First-Degree Relatives of People With Schizophrenia: Toward a Neurobiology of Vulnerability to Schizophrel(