Having been a fairly dormant specialty for many decades, in recent years there has been a remarkable increase in activity in Neuro-oncology from basic science through to the clinics. Reflecting this there have been considerable advancements in the understanding of the biology of CNS malignancies which have infirmed the development of many novel and successful therapies. This work aims to bring together the scattered literature on the new concepts in neuro-oncology for the benefit of those in the field. The book moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice.
This work consolidates and elucidates the scattered literature on the new concepts in neuro-oncology. It moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice.
Part I??? Scientific Foundations
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1.?????? Classification of Gliomas
??????????????? Pieter Wesseling
2.?????? Epigenetics and Brain Cancer
??????????????? Davide Sciuscio and Monika E. Hegi
3.?????? Astrocyte Differentiation from Oligodendrocyte Precursors
??????????????? Akiko Nishiyama
4.?????? Stem Cells and Brain Cancer
??????????????? Sara G.M. Piccirillo
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Part II??? ??? Models of Brain Cancer
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5.?????? In Vitro Models of Brain Cancer
??????????????? David J. Ryan and Colin Watts
6.?????? Mouse Models of Glioma Pathogenesis: History and State of the Art
??????????????? Sebastian Branlc,