endoCANNABINOIDS Actions at Non-CB1/CB2 Cannabinoid Receptors [Hardcover]

This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.

Featuring research from many of the leading scientists in the field, this volume complements recent publications describing cannabinoids, focusing on the physiological and therapeutic characteristics of compounds that modulate CB1 and CB2 receptor function.

PART I: Overview of Non-Cannabinoid Receptors

Chapter 1: Overview of Non-Classical Cannabinoid Receptors
Grzegorz Godlewski and George Kunos

Chapter 2: Overview of Non-Cannabinoid Receptors: Chemistry and Modeling
Evangelia Kotsikorou and Patricia Reggio

PART II: G-Protein Coupled Receptors

Chapter 3: GPR55 in the CNS
Hui-Chen Lu, Jane E. Lauckner, John W. Huffman, Ken Mackie

Chapter 4: The Role of GPR55 in Bone Biology
Lauren S. Whyte and Ruth A. Ross

Chapter 5: The Role of GPR55 in Cancer
Clara Andradas, Mar?a M Caffarel, Eduardo P?rez-G?mez, Manuel Guzm?n and Cristina S?nchez

Chapter 6: GPR18 and NAGly signaling: New members of the endocannabinoid family or distant cousins?
Douglas McHugh and Heather B Bradshaw

Chapter 7: Cannabinoid Signaling Through Non CB1/Non CB2 GPCR Targets in Microglia
Neta Rimmerman, Ewa Kozela, Rivka Levy, Zvi Vogel, Ana Juknat

PART III: Ion Channels&l³x