Endocrine Oncology [Paperback]

Stephen P. Ethier and a panel of leading investigators comprehensively analyze the cellular, molecular, and endocrine factors in the development of cancers of the breast, prostate, endometrium, and ovary. Concentrating on defining the most important unresolved issues in the field, the authors review how steroid hormones function to regulate normal mammary gland homeostasis in humans, with particular emphasis on the roles of estrogen, progesterone, and growth factors. Comprehensive and up-to-date, Endocrine Oncology offers both basic and clinical researchers not only the latest molecular and cellular findings on endocrine cancers, but also a powerful critical analysis that will prove invaluable to all endocrinologists and oncologists working in the area today.Stephen P. Ethier and a panel of leading investigators comprehensively analyze the cellular, molecular, and endocrine factors in the development of cancers of the breast, prostate, endometrium, and ovary. Concentrating on defining the most important unresolved issues in the field, the authors review how steroid hormones function to regulate normal mammary gland homeostasis in humans, with particular emphasis on the roles of estrogen, progesterone, and growth factors. Comprehensive and up-to-date, Endocrine Oncology offers both basic and clinical researchers not only the latest molecular and cellular findings on endocrine cancers, but also a powerful critical analysis that will prove invaluable to all endocrinologists and oncologists working in the area today.Estrogen Receptor in Mammary Gland Physiology, Elizabeth Anderson, Robert B. Clarke, and Anthony Howell. Multiple Facets of Estrogen Recptor in Human Breast Cancer, Leigh C. Murphy, Etienne Leygue, Helmut Dotzlaw, Amanda Coutts, Biao Lu, Aihua Huang, and Peter H. Watson. Progesterone Receptors in Normal and Neoplastic Breast, Rosemary L. Balleine, Patricia A. Mote, Sybille M. N. Hunt, Eileen M. McGowan, and Christine L. Clarke. Pathogenesis of Estrogen Recl3³