Endometriosis Pathogenesis and Treatment [Hardcover]

Endometriosis is one of the most common gynecological diseases, causing?pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it.?This book provides a clear insight into?the pathogenesis and pathophysiology of endometriosisessential?information for?clinicians?intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.??

Preface.- PART`. INTRODUCTION.- Endometriosis: a mysterious disease.- Parta. BASIC SCIENCE.- Pathological aspect and pathogenesis of endometriosis.- Visible and invisible (occult) endometriosis.- Role of stem cells in the pathogenesis of endometriosis.- Role of NK cells in endometriosis.- Macrophages in Pathophysiology of Endometriosis.- Inflammation and Cytokines in Endometriosis.- Epigenetics in endometriosis.- Roles of Prostaglandin E2 in Endometriosis.- Sex steroids and endometriosis.- Aromatase expression in endometriosis and its significancl®