Epigenetics and Chromatin [Paperback]

Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence.

This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.

This book gives a comprehensive overview on chromatin structure and function in combination with an epigenetic view. It offers an updated collection of papers treating epigenetic phenomena in mammals, insects and plants.

Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence.

This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.

Chromatin Remodeling Factors and DNA Replication.- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila.- How to Pack the Genome for a Safe Trip.- Chromatin Modifications on the Inactive X Chromosome.- Chromatin Mechanisms in Drosophila Dosage Compensation.- DNA Methylation in Epigenetic Control of Gene Expression.- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications.- Devl³Z