Epilepsy Models, Mechanisms and Concepts [Paperback]

This book considers a number of major concepts and models in epilepsy research, to advance understanding of the basic mechanisms involved.This volume concentrates on the concepts and models of epilepsy research. It describes and discusses the relevant models used to address critical questions, and reviews the most up-to-date issues in this rapidly advancing field. Taking a conceptual approach to the subject, it provides a solid framework within which to understand the emerging issues. It will be a valuable source of reference and knowledge for basic neuroscientists, as well as for neurologists and neurosurgeons with a special interest in the epilepsies.This volume concentrates on the concepts and models of epilepsy research. It describes and discusses the relevant models used to address critical questions, and reviews the most up-to-date issues in this rapidly advancing field. Taking a conceptual approach to the subject, it provides a solid framework within which to understand the emerging issues. It will be a valuable source of reference and knowledge for basic neuroscientists, as well as for neurologists and neurosurgeons with a special interest in the epilepsies.Advances in epilepsy research are occurring at a rapid rate, resulting in a bewildering wealth of data. The implications of this new knowledge for future research and clinical practice can be confusing. This volume concentrates on the concepts and models of epilepsy that have been developed as a result of this research. Written by prominent researchers in the field, it describes and discusses the relevant models used to address critical questions, and reviews the most up-to-date issues. Chapters focus on the pathways and mechanisms through which seizure activity is initiated and spread, in both normal and abnormal brain tissues, and discuss the special properties of epileptogenesis in the immature brain. In a field in which rapid advances lead to constant update of empirical data, this book takes a conceplc*