Essential Concepts in Toxicogenomics [Paperback]

The field of toxicogenomics has been growing quickly. This informative and cutting-edge book collects reviews, opinion pieces and case studies from this dynamic field with a focus on its application to pharmaceuticals.

Toxicogenomics and Classical Toxicology: How to Improve Prediction and Mechanistic Understanding of Human ToxicityDonna L. Mendrick Use of Traditional Endpoints and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic ToxicologyWayne R. Buck, Jeffrey F. Waring, Eric A. Blomme. Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic ApplicationsKarol L. Thompson and Joseph Hackett Role of Statistics in ToxicogenomicsMichael Elashoff Predictive Toxicogenomics in Preclinical DiscoveryScott A. Barros and Rory B. Martin In Vivo Predictive ToxicogenomicsMark W Porter Bioinformatics: Databasing and Gene AnnotationLyle D. Burgoon and Timothy R. Zacharewski Microarray Probe Mapping and Annotation in Cross-Species Comparative ToxicogenomicsJohn N Calley, William B Mattes, and Timothy Ryan Toxicogenomics in Biomarker DiscoveryMarc F. DeCristofaro and Kellye K. Daniels From Pharmacogenomics to Translational BiomarkersDonna L. Mendrick Public Consortium Efforts in ToxicogenomicsWilliam B. Mattes Applications of Toxicogenomics to Nonclinical Drug Development  Regulatory Science ConsiderationsFrank D. Sistare and Joseph J. DeGeorge

From the reviews:

Essential Concepts in Toxicogenomics is a collections of reviews, opinion pieces and case studies written by experts in the field. & gives good coverage of whole field of toxicogenomics. & If you want to get up to steam with this area then & it is certainly worth reading this book. (James Sidaway, BTS Newsletter, Winter, 2008)

The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the natló