Essentials of Antimicrobial Pharmacology A Guide to Fundamentals for Practice [Paperback]

Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.Chapter 1. IntroductionMeasures of Antibiotic EffectAntibiotic AdministrationDistribution and EliminationSensitivity TestingDose-Response RelationshipsResistanceChapter 2. Antibacterial AgentsCell Wall Active AgentsAntifolate AgentsAminoglycosides/AminocyclitolsAntiribosomal AgentsTopoisomerase InhibitorsMiscellaneous AgentsAntimycobacterial AgentsInvestigational AgentsCombination Antibacterial lÃ#