Focal Controlled Drug Delivery [Hardcover]

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book?will?review advances in treatment options for diseases localized at a certain tissue or organ.

1. Biodegradable Polymers for Focal Delivery Systems

Wahid Khan, Venu Gopala Swami Challa, Robert Langer, and Abraham J. Domb

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2. Implantable Medical Devices

Wahid Khan, Eameema Muntimadugu, Michael Jaffe, and Abraham J. Domb

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3. Systemic Targeting Systems-EPR Effect, Ligand Targeting Systems

Prasad V. Pawar, Abraham J. Domb, and Neeraj Kumar

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4. Liposomal formulations for Focal and Targeted Drug Delivery in Cancer and Other Diseases

Sean Essex and Vladimir Torchilin

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5. Polymer Drug Conjugate in Focal Drug Delivery

Rajan Swami, Dinesh Kumar, Wahid Khan, Ramakrishna Sistla, Nalini Shastri

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