Free Radicals and Antioxidant Protocols [Paperback]

This cutting-edge and updated book offers methods for the rapid detection of RONs and redox stress. It includes in-depth analysis of natural and synthetic antioxidants, and also of DNA oxidation, oxidative lipidomics, and biomarkers.

ContentsPrefaceContributorsPart I Reactive Oxygen and Nitrogen Species1. In Vivo Imaging of Free Radicals and OxygenDeepti S. Vikram, Brian K. Rivera, and Periannan Kuppusamy2 . In Vivo Measurement of Tissue Oxygen using Electron Paramagnetic Resonance Spectroscopy with Oxygen-sensitive Paramagnetic Particle, Lithium PhthalocyanineF. Hyodo, S. Matsumoto, E. Hyodo, A. Matsumoto, K. Matsumoto, and M. C. Krishna3. Measurement of Plasma Nitrite by ChemiluminescenceEnika Nagababu and Joseph M Rifkind4. Determination of Glutathione, Mitochondrial Transmembrane Potential, and Cytotoxicity in H9c2 Cardiomyoblasts Exposed to Reactive Oxygen and Nitrogen SpeciesK. Sathishkumar, Xueli Gao, Achuthan C. Raghavamenon, Narasimham L. Parinandi, and Rao M. UppuPart II Natural and Synthetic Antioxidants5. Phenolic Acids and Flavonoids: Ocurrence and Analytical MethodsConstantine D. Stalikas6. Design, Synthesis, and Action of Antiatherogenic AntioxidantsOsamu Cynshi, Kunio Tamura, and Etsuo Niki7. Preparation of Drug-Loaded Polymeric Nanoparticles and Evaluation of the Antioxidant Activity against Lipid PeroxidationAdriana R. Pohlmann, Scheila Rezende Schaffazick, T?nia B. Creczynski-Pasa, and S?lvia S. Guterres8. Nanoparticle and Iron Chelators as a Potential Novel Alzheimer TherapyGang Liu, Ping Men, George Perry, and Mark A. Smith9. Synthesis and Characterization of Polymer Nanocarriers for the Targeted Delivery of Therapeutic EnzymesEric Simone, Thomas Dziubla , Vladimir Shuvaev, and Vladimir R. Muzykantov10. Assessment of Antioxidant Activity of Eugenol In Vitro and In VivoEnika Nagababu, Joseph M. Rifkind, Sesikeran Boindala, andLakshmaiah NakkaPart III Cellular Oxidative Stress11. The Generation of Stable Oxidative Stress-ResistanlCÐ