Function and Biosynthesis of Lipids [Paperback]

In memoriamProfessor Werner Seubert.- A short history of the biochemistry of lipids in Argentina (Opening address).- Opening Lecture.- The role of dolichol in protein glycosylation.- I. Lipid Involvement in the Biogenesis of Membranes.- (A) Biosynthesis of fatty acids.- The role of lipid in stearyl CoA desaturation.- Biosynthetic pathways of polyunsaturated fatty acids.- The specificity of mammalian desaturases.- Regulation of the ?9 desaturation.- Regulatory function of ?6 desaturaseKey enzyme of polyunsaturated fatty acid synthesis.- Saturated and mono-unsaturated fatty acid biosynthesis in brain: relation to development in normal and dysmyelinating mutant mice.- Protein factor involved in fatty acid desaturation of linoleic acid.- Biosynthesis of lipids in tumoral cells.- Specificity of ?6 desaturase. Effect of chain length and number of double bonds.- Fetal accumulation of long-chain polyunsaturated fatty acids.- Materno-fetal transfer of 14C linoleic and arachidonic acids.- (B) Biogenesis and organization of cellular membranes.- On the asymmetric composition of plasma membranes.- Influence of the lipid environment on the properties of rhodopsin in the photoreceptor membrane.- Approaches to the biochemistry of regeneration in the central nervous system.- 3-D-(?)Hydroxybutyrate dehydrogenase from rat liver mitochondria  Purification and interaction with phospholipids.- The role of phospholipids in Na-K ATPase.- Interactions with phospholipid monolayers of lipids and water-soluble compounds that induce membrane fusion.- The lipid composition and Ca transport function of sarcoplasmic reticulum (SR) membranes during development in vivo and in vitro.- Lipid metabolism during development in insects.- Composition and metabolism of phospholipids during early stages of vertebrate embryonic development.- II. GlycosphingolipidsGangliosides.- Structural specificity of gangliosides.- The biosynthesis of brain gangliosidesEvidence for a transient pool and an end produlÎ