An integrated textbook of medical neuroscience, this book coherently presents the anatomy, physiology, and biochemistry of the human nervous system. The neuroanatomy is presented in a way that is integrated with a modern presentation of cellular neurophysiological systems, neuroscience, and cellular, molecular, and developmental neuroscience. Clinical correlations are provided wherever appropriate.An integrated textbook of medical neuroscience, this book will make a coherent presentation of anatomy, physiology, and biochemistry of the human nervous system. The neuroanatomy will be presented in a way that is integrated with a modern presentation of cellular neurophysiological systems, neuroscience, and cellular, molecular, and developmental neuroscience. Clinical correlations will be provided wherever appropriate.I The Ground Plan of the Nervous System.- 1. Ground Plan of the Nervous System I Principles of Central Nervous System Development.- 2. Ground Plan of the Nervous System II Levels of the Neuraxis.- 3. Central Nervous System Vasculature, Blood-Brain Barrier, and Cerebrospinal Fluid.- 2 Cellular Basis of Neuronal Signaling.- 4. Cell Biology of Neurons.- 5. Cell Biology of Glia.- 6. Presynaptic Mechanisms Underlying Neurotransmitter Synthesis, Storage, Release and Inactivation.- 7. Postsynaptic Mechanisms: Neurotransmitter Receptors and Signal Transduction Cascades.- 8. Neuronal Integration.- 3 The Somatosensory System.- 9. Somatic Sensation I Peripheral Receptors and Primary Afferent Neurons.- 10. Somatic Sensation II Ascending Pathways From the Spinal Cord and Brainstem to the Thalamus.- 11. Somatic Sensation III The Physiology of Somatic Sensation.- 12. Somatic Sensation IV Pain.- 4 The Motor System.- 13. Motor System I The Anatomical Organization of the Motor System.- 14. Motor System II Segmental Control of Movement: The Motor Unit and Segmental Reflexes.- 15. Motor System III Supraspinal Control of Movement.- 16. The Basal Ganglia.- 17. Role of the CerebellCĪ