Gene-Based Therapies for Cancer [Paperback]

Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.This volume on developing gene therapies for many cancers emphasizes translational gene therapy approaches. Chapters include specific gene delivery technologies and their application to various cancers with extensive discussions of ongoing clinical trials.Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.Gene-based Therapies for Cancer1. RNAi: A New Paradigm in Cancer Gene Therapy. Edna M. Mora, Selanere L. Mangala, Gabriel Lopez-Berestein, Anil K. Sood2. Gene-based Therapy for Cancer: Brain tumors. Hong Jiang, Juan Fueyo3. Gene Therapy of Prostate Cancer. Svend O. Freytag, Hans Stricker, Benjamin Movsas, Mohamed Elshaikh, Ibrahim Aref, Kennetl“0