Genetic Toxicology Principles and Methods [Hardcover]

The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously important area of study.? The volume covers three basic areas: the scientific basis of the discipline, the methodologies of the main test assays, and the application of the methods, all aimed primarily at scientists in the safety departments of the industries working with both natural and synthetic chemicals.? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Intuitive and cutting-edge, Genetic Toxicology: Principles and Methods provides crucial support to both laboratory workers in providing quality information on the appropriate application of techniques and to study directors in their assay selection and protocol design in this vital field.

Evaluating potential mutagenic activity is a critical step in assessing the safety of both new and pre-existing chemical types. In this book, expert contributors help to satisfy the demand for education in this vitally important field of research.

1. The Application of Structure Activity Relationships to the Prediction of the Mutagenic Activity of Chemicals

??????????? Philip Judson

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2. Bacterial Mutagenicity Assays: Test Methods

??????????? David Gatehouse

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3. The Mousls#