Genetics of Translation New Approaches [Paperback]

Translation, i.e. protein synthesis, studied from a genetic viewpoint is illustrated in this volume, demonstrating how researchers are employing both classical genetic and recombinant DNA techniques in studying the components, mechanisms, regulation and accuracy of protein synthesis. Both the prokaryotic (especially Escherichia coli) and eukaryotic (especially Saccharomyces cerevisiae) system are discussed, presenting both new information and the new genetic approaches available. This book does not concentrate on one particular aspect of translation, but provides an ideal overview of the genetic approaches for dissecting the translation process as well as the current rapid advances made in the field through the use of in vitro genetics.Proceedings of the NATO Advanced Research Workshop on Genetics of Translation - New Approaches, held in Aussois, France, May 21-26, 1987Translation, i.e. protein synthesis, studied from a genetic viewpoint is illustrated in this volume, demonstrating how researchers are employing both classical genetic and recombinant DNA techniques in studying the components, mechanisms, regulation and accuracy of protein synthesis. Both the prokaryotic (especially Escherichia coli) and eukaryotic (especially Saccharomyces cerevisiae) system are discussed, presenting both new information and the new genetic approaches available. This book does not concentrate on one particular aspect of translation, but provides an ideal overview of the genetic approaches for dissecting the translation process as well as the current rapid advances made in the field through the use of in vitro genetics.1: Integration of the Ribosome Cycle in Bacterial Cell Physiology.- Ribosomal RNA.- 2: Probing Ribosome Function Through Mutagenesis of Ribosomal RNA.- 3: Antibiotic Resistance Mutations in Escherichia coli Ribosomal RNA Genes and Their Uses.- 4: Feedback Rel<