This concise pocketbook will provide readers with an overview and background of meningococcal disease, treatment options and emerging therapies, and methods of prevention. The book was originally commissioned due to recent developments in vaccinations to prevent meningococcal disease. This book reviews the disease progression and associated risk factors; its pathogenesis and diagnosis; methods of treatment and prevention, both current and emerging; and the future directions of meningococcal disease management. The book is ideal for busy healthcare professionals, as it covers all aspects of the disease and its treatment in a condensed and manageable format, whilst including the most up-to-date treatment guidelines and algorithms.
1. Introduction and epidemiology of meningococcal disease
Neisseria meningitidis
Disease surveillance
Case fatality and sequelae
Epidemiology of meningococcal disease
Capsular groups causing disease
Current issues
Summary points
References
2. Carriage and transmission of Neisseria meningitidis
Introduction
Detecting the carrier state
The natural history of meningococcal carriage
Epidemiology of carriage
Other Neisseria species
Effect of vaccination on carriage
Summary points
References
3. Pathogenesis of invasive disease
Introduction&ll#,
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