Hans Krebs Volume 1 The Formation of a Scientific Life, 1900-1933 [Hardcover]

This is the first volume of a comprehensive scientific biography of Hans Krebs, one of the world's foremost biochemists. It treats his childhood, his medical education and scientific apprenticeship under Otto Warburg, his emergence as an independent investigator, and his discovery of the urea cycle in 1932. This early achievement, and his discovery of the citric acid cycle, are viewed as foundations for the modern structure of intermediary metabolism. During the writing of this fascinating history, the author had access to a complete set of Krebs' laboratory notebooks that reveal the daily dimensions of scientific creativity. Based in addition on many personal interviews with its subject, the Krebs biography is certain to interest and intrigue biochemists and historians of science alike. Volume 2: Hans Krebs: Architect of Intermediary Metabolism 1933-37, will appear in spring, 1993.

1. Intermediary Metabolism in the First Third of the Twentieth Century
2. Boyhood in Hildesheim
3. Outward Movement
4. Clinical Years
5. The Research Apprentice
6. Initiative and Dependence
7. Moves Toward Autonomy
8. Freiburg: The Foundation of a Career
9. The Ornithine Effect
10. The Formation of Urea
11. The Rewards of Success
12. The Brief Life of a Freiburg School of Metabolism
13. Reflections on the Formation of a Scientific Life

In this large first volume....Holmes reconstructs the education and early career of a remarkable scientist with equally remarkable clarity, comprehensiveness, and detail....This magnificent biography demonstrates, as few books do, the intimate relations between personality and science. --Science

Volume 1 covers Krebs's early life and education, including the beginnings of his research career....Volume 2 covers the time from his arrival in England to publication of the paper on the citric acid cycle in 1937....These volumes have much to say to specialist and nonspecialist alike aboutlC(