This book describes the principles underlying targeted hormonal treatments, assesses the actions of new and established agents, and illustrates the new applications of hormonal chemoprevention for breast cancer.
An Introduction to the Regulation of Sex Steroids for the Treatment of CancerV. Craig Jordan and Barrington J. A. FurrPart I. Preclinical AntiestrogensAntiestrogens and the Cell CycleColin K. W. Watts, Owen W. J. Prall, Jason S. Carroll, Nicholas R. C. Wilcken, Eileen M. Rogan, Elizabeth A. Musgrove, and Robert L. SutherlandDrug Resistance to AntiestrogensRuth M. O'Regan, Anait S. Levenson, Gale M. England, Kathy A. Yao, Henry D. Muenzner, Hiroyuki Takei, and V. Craig JordanMechanisms of Liver Carcinogenesis by AntiestrogensDavid H. PhillipsThe Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepatocarcinogenesis in the RatYvonne P. Dragan and Henry C. PitotPreclinical Studies of Raloxifene and Related CompoundsRobin Fuchs-Young. Pure Antiestrogens, Alan E. WakelingPart II. Antiestrogens: ClinicalTamoxifen for the Treatment of Breast CancerV. Craig JordanClinical Utility of New AntiestrogensRuth M. O'Regan and William J. GradisharBreast Cancer Prevention with AntiestrogensMonica Morrow and V. Craig JordanPart III. Inhibition of Estrogen SynthesisAromatase InhibitorsPaul E. Goss and Caroline C. ReidClinical Utility of Aromatase InhibitorsK. Shenton, Mitchell Dowsett, and Michael DukesLH-RH Agonists for the Treatment of Breast Cancer: Development and Current StatusRoger W. BlameyPart IV. Androgen and Androgen WithdrawalMolecular Action of AndrogensShutsung Liao, Junichi Fukuchi, and Yung-Hsi KaoSteroidal AntiandrogensFritz H. Schr?der and Albert RadlmaierNonsteroidal AntiandrogensGeert J. C. M. Kolvenbag and Barrington J. A. FurrLH-RH Agonist Role in Prostate Cancer ManagementAmir V. KaisaryPart V. Perspective on ProgressRecent Progress in Breast Cancer ResearchV. Craig Jordan and Barrington J. A. Furr
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