Human Embryonic Stem Cells [Paperback]

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.Part I. PolicyEthical Issues Associated with Pluripotent Stem CellsSteve UsdinA Researcher's Guide to Federally Funded Human Embryonic Stem Cell Research in the United StatesGregory J. DowningIntellectual Property of Human Pluripotent Stem CellsMark L. RohrbaughPart II. Types of Pluripotent CellsEmbryonal Carcinoma Cells: The Malignant Counterparts of ES and EG CellsJonathan S. Draper, Harry Moore, and Peter W. AndrewsHuman Pluripotent Cells from Bone MarrowFelipe Prosper and Catherine M. VerfaillieProtocols for the Isolation and Maintenance of Human Embryonic Sls’