Hypoxia Translation in Progress [Paperback]

The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before translational medicine was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies.

This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include:

• Epigenetic Variations in Hypoxia
  High Altitude Adaptation
  
• Hypoxia and Sleep
  
• Hypoxia and the Brain
  
• Molecular Oxygen Sensing
  
• Physiological Responses to Hypoxia

Epigenetic Mechanisms as anInterface Between the Environment and Genome.- Developmental Origins of HypoxicPulmonary Hypertension and Systemic Vascular Dysfunction: Evidence fromHumans.- Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibitionof Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: TherapeuticImplications.- Epigenetics in Cardiovascular Regulation.- Why Are High AltitudeNative So Strong at Altitude?: Maximal Oxygen Transport to the Muscle Cell inAltitude Natives.- Novel Insights into Cardiovascular Regulation in Patientswith Chronic Mountain Sickness.- Why Are High Altitude Nal£,