Immunoinformatics [Hardcover]

In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

IMGT-ONTOLOGY, IMGT? Databases, Tools, and Web Resources for Immunoinformatics.- IMGT Standardization for Molecular Characterization of the T-cell Receptor/Peptide/MHC Complexes.- Structural Immunoinformatics.- In Silico QSAR-Based Predictions of Class I and Class II MHC Epitopes.- Allergen Bioinformatics.- Immunoinformatics Applied to Modifying and Improving Biological Therapeutics.- Plasticity of Dendritic Cell Transcriptional Responses to Antigen: Functional States of Dendritic Cells.- Understanding the Immune System by Computer-Aided Modeling.- Simulation of HIV-1 Molecular Evolution in Response to Chemokine Coreceptors and Antibodies.- MUTANT MOUSE: bona fide Biosimulator for the Functional Annotation of Gene and Genome Networks.

Christian Sch?nbach is currently an Associate Professor (Genetics and Genomics) at Nanyang Technological University (Singapore). Until recently he was Team Leader of the Immunoinformatics Team at the RIKEN Genomic Sciences Center (Japan). His research on decoding mouse genome information employs both computational and experimental methods. He obtained is higher education at University of W?rzburg, SUNY Albany, University of T?bingen, Max-Planck Institute for Biology, and UCSD. He holds a doctor degree in Genetics obtained through immunogenetics research under Jan Klein at the Max-Planck Institute for Biology. He completed his post-doctoral training in experimental and computational immunology with Masafumi Takiguchi and Kohji Eglã)